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CHOLESTEROL | BEYOND THE NUMBERS

Writer's picture: Mark OfferdahlMark Offerdahl

Cholesterol has long been a topic of concern, often oversimplified to the mantra "lower LDL, better health." However, this perspective might be missing the forest for the trees. Here, we're not providing medical advice but rather a broader view of cholesterol's role in our health.



The Complexity of Lipoproteins


The conventional narrative focuses heavily on LDL cholesterol as the villain of heart health. But what if we told you that there's more to the story? Lipoproteins come in various forms – from VLDL to HDL, including different patterns of LDL like A and B. While these types and their quantities are important, the quality of these particles might hold the key to understanding true cardiovascular health risks.


Research highlights that LDL, when unmodified or naturally occurring, doesn't inherently lead to atherosclerosis. Instead, it's the oxidation of LDL that transforms it into a potential threat, contributing to the formation of artery-clogging plaques. This suggests that focusing solely on LDL levels might be an oversimplification of a much more complex biochemical process.


The Role of Oxidation and Inflammation


Oxidative stress turns LDL into oxidized LDL (oxLDL), which is implicated in the initiation and progression of atherosclerosis. This process doesn't just happen in isolation; it's often facilitated by a cascade of metabolic imbalances:


  • Dietary Factors: Diets high in linoleic acid, found in industrial seed oils, can promote LDL oxidation and inflammation.

  • Lifestyle Choices: Factors like sedentary behavior, poor sleep, chronic stress, and excessive alcohol intake can skew metabolic health, leading to increased inflammation and oxidative stress.



Beyond Traditional Metrics


To truly gauge cardiovascular health, looking at more than just LDL cholesterol is essential:


  • Oxidized LDL (oxLDL): Measuring oxLDL can provide insights into actual risk levels since it's this form that contributes directly to plaque formation.

  • Linoleic Acid Levels: Monitoring linoleic acid in blood can guide dietary adjustments to reduce inflammation and oxidation.

  • Triglycerides/HDL Ratio: This ratio can be a more practical indicator of metabolic health, with lower ratios signaling better health outcomes.

  • Fasting Insulin: High levels might indicate insulin resistance, a significant precursor to heart disease.

  • Visceral Fat Measurement: Excessive visceral fat correlates with increased cardiovascular risk.

  • Endothelial Function Tests: Tools like MaxPulse or EndoPAT assess blood vessel health, offering a direct measure of vascular disease risk.


A Holistic Dietary Approach


Considering metabolic health comprehensively often points towards a diet rich in nutrients that can naturally combat oxidative stress and inflammation. An animal-based diet, particularly one that includes nutrient-dense organs, might offer the necessary nutrients to support this health paradigm. Supplementation might also play a role where dietary intake falls short.


Conclusion


Cholesterol management isn't just about numbers. It's about understanding the quality of those numbers, the context of metabolic health, and the lifestyle factors at play. While this perspective might challenge traditional views, it opens up a dialogue about how we approach cardiovascular health more holistically. For personalized advice, always consult with healthcare providers who appreciate this nuanced approach to health.


Remember, this discussion isn't just about altering dietary fats or taking pills; it's about fostering a lifestyle that supports the body's natural defences against disease. Explore further with professionals who align with a metabolic health-focused practice for guidance tailored to your unique health journey.






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